This species demonstrates great variation in its burrow construction, but usually there is one principal gallery with a constant depth that forms the major axis. Tunnels have an average of thirteen openings, with a range of five to 24, and vary in length from 70 to 130 cm. There are one or two nests of dried grass per tunnel (Altuna 1983).  This species lives in coastal sandy environments (de Freitas 2016) and prefers sand dune habitats but ranges inland as well (Queirolo pers. comm.). It uses a broad range of soil types (Lessa pers. comm.). It lives in predominantly sandy soils with variable clay-loam fraction (Lessa and Langgruth 1983, cited in Mora et al., 2003). In the west it inhabits hard soils and in the east it also inhabits softer soils, close to lakes and lagoons, including sand dunes (Lessa pers. comm).

This species is known from Soriano, San Jose and Colonia departments in Uruguay (Woods and Kilpatrick 2005, Acton 2013) and occurs below 200 m asl in altitude.

No specific conservation measures are in place to protect this species. Some protected areas have been created to conserve coastal lagoons and these may indirectly benefit Ctenomys pearsoni (Lessa pers. comm).