This species is typically associated with lowland tropical moist forest, although it has also been recorded from swamp forest and mosaic forest-grassland habitats (Bergmans 1997). It appears to be confined to forest with a closed canopy, but within this habitat it has been recorded suspended from plantain leaves, shrubs and inside human habitations (Rosevear 1965, Weber et al. 2009). It commonly forages within banana plantations and other cultivated areas adjacent to forests (Grubb et al. 1998, Weber et al. 2009). Little is known about roosting behavior, however, it does not seem to roost in groups. This obligate nectivorous bat species feeds on nectar as well as pollen of several plants (Petterssen 2005, Weber et al. 2009).

This species ranges throughout much of Central Africa. It is distributed from Cameroon in the West and from here south and east into Equatorial Guinea, Central African Republic, Gabon, Republic of Congo, Angola, Democratic Republic of the Congo and western Uganda. The range boundary of this species, particularly west of Cameroon, is currently unclear, and it might extend as far as the Dahomey gap in Nigeria and Benin (Nesi et al. 2013). There may be geographic overlap with M. azagnyi in these two countries, but it is yet unresolved if the two Megaloglossus species occur sympatrically. Records from Nigeria (Happold 1987) and Benin (Djossa et al. 2008, Weber et al. 2009) are thus not assignable to M. woermanni or M. azagnyi based on the data available.

There appear to be no direct conservation measures in place, but the species occurs in a number of protected areas. Understanding ecology and distribution of this species should be subject to future research.