The Calabar Angwantibo is most often found in areas of dense, low undergrowth with abundant lianas and vines below 5 m in the understorey of primary and secondary rainforest; it particularly favours the growth that springs up in clearings, trees falls, and along forest edges (Jewell and Oates 1969). Therefore, wherever it is already established, small-scale forest clearance, selective tree-felling and road-making probably favour this species. In such areas it can becomes relatively abundant in thickets and patches of dense secondary growth. Its diet is invertebrates and fruits; based on the ecology of its sister taxon Arctocebus aureus in Gabon, it is likely that caterpillars form an important part of its diet. This species is able to produce two single young in a year, with a minimum inter-birth interval of about 4.5 months (Oates and Ambrose 2013).